منابع مشابه
Small Cells—Big Future
Every living organism—including Earth's simplest life form, the bacterium—is loaded with molecular devices that are breathtaking in their design, complexity, and efficiency. Eukaryotes have long been known to possess sophisticated subcellular architecture in which DNA, RNA, and proteins are localized to the right place at the right time. Bacteria, in contrast, have until recently been thought t...
متن کاملSmall Molecule, Big Prospects: MicroRNA in Pregnancy and Its Complications
MicroRNAs are small, noncoding RNA molecules that regulate target gene expression in the posttranscriptional level. Unlike siRNA, microRNAs are "fine-tuners" rather than "switches" in the regulation of gene expression; thus they play key roles in maintaining tissue homeostasis. The aberrant microRNA expression is implicated in the disease process. To date, numerous studies have demonstrated the...
متن کاملSMPDB 2.0: Big Improvements to the Small Molecule Pathway Database
The Small Molecule Pathway Database (SMPDB, http://www.smpdb.ca) is a comprehensive, colorful, fully searchable and highly interactive database for visualizing human metabolic, drug action, drug metabolism, physiological activity and metabolic disease pathways. SMPDB contains >600 pathways with nearly 75% of its pathways not found in any other database. All SMPDB pathway diagrams are extensivel...
متن کاملEthylene and Metal Stress: Small Molecule, Big Impact
The phytohormone ethylene is known to mediate a diverse array of signaling processes during abiotic stress in plants. Whereas many reports have demonstrated enhanced ethylene production in metal-exposed plants, the underlying molecular mechanisms are only recently investigated. Increasing evidence supports a role for ethylene in the regulation of plant metal stress responses. Moreover, crosstal...
متن کاملUnited Statistical Algorithms, Small and Big Data, Future of Statistician
Role of big idea statisticians in future of Big Data Science. United Statistical Algorithms framework for comprehensive unification of traditional and novel statistical methods for modeling Small Data and Big Data, especially mixed data (discrete, continuous). Goal: Model (X, Y ) by nonparametrically estimating conditional mean E[Y |X = x] and conditional quantile Q(u;Y |X = x). Modeling exampl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Council
سال: 2019
ISSN: 2658-5790,2079-701X
DOI: 10.21518/2079-701x-2019-3-89-91